Noninvasive 635nm LLLT was significantly more effective at reduction of arm circumference than sham treatments at every tested time point. This study showed significant results without any apparent confounding variables. Subjective assessments were significantly positive for the treatment group. No pain or discomfort of any kind was associated with treatment and no adverse events were reported by any subject throughout the study. Together, these results indicate low-level energy laser treatment appears to be a safe and effective method for noninvasively reducing upper arm circumference.